Canadian College of Medical Geneticists (CCMG) points to consider: resuming genetic services in a pandemic-a summary

The COVID-19 pandemic has disrupted the availability of genetic care in Canada. With the general public well being effort to flatten the curve, many clinics have moved to digital take care of choose populations of sufferers whereas triaging and suspending others. As genetic services are requested to steadily resume, a roadmap is required to guarantee medical care selections for at-risk sufferers are clear and equitable, that postponed care is resumed and that sufferers with or ready for a genetic prognosis are usually not disproportionately affected or deserted.

The objective of this doc is to spotlight the guiding moral ideas and stakeholder concerns in resuming genetic services to assist information the competing wants going ahead of each limiting exposures whereas sustaining high-quality care. Considerations highlighted are (1) setting of follow, (2) nature of seek the advice of, (3) affected person components, (4) supplier components, and (5) laboratory components. The supposed customers are these offering genetic care in a Canadian context with the popularity that there are clinic-specific and regional variations that may affect decision-making.

While particular to the Canadian context, the moral ideas used to information these selections could be related for consideration in different jurisdictions. In the final decade, machine studying (ML) methods have been broadly utilized to determine completely different illnesses. This facilitates an early prognosis and will increase the possibility of survival. The majority of medical data-sets are unbalanced. Due to this, ML classification methods give biased classification over the bulk class. In this paper, a novel health perform in Genetic Programming, for medical knowledge classification has been proposed that handles the issue of unbalanced knowledge.

Genetic Testing and Counseling in Metabolic Liver Disease: An Interactive Lecture for Medical Students

Medical college students have restricted alternatives to find out about present genetic testing. This session offered publicity to differing types of testing and the complicated points that physicians could encounter when counseling sufferers on correct testing and decoding outcomes. We designed a 1-hour interactive lecture for second-year medical college students. We introduced an outline of the subject, then utilized the ideas to particular problems and circumstances. The session was additionally recorded in order that further college students not in attendance may watch, and was obtainable to 151 college students in 2018 and 333 college students in 2019.
Students had been requested to reply questions concerning circumstances utilizing an viewers response system, and we used their responses as the idea for our in-class dialogue. This session has been held twice, with 25 college students attending in 2018 and 31 college students in 2019. Four benchmark medical data-sets named power kidney illness (CKD), fertility, BUPA liver dysfunction, and Wisconsin diagnostic breast most cancers (WDBC) have been taken from the University of California (UCI) machine studying repository. Classification is finished utilizing the proposed method.
Students answered questions through viewers response system. There was a vary of 47%-100% of college students giving the proper solutions in 2018, and 55%-93% in 2019. Exam questions masking genetic counseling points had been answered accurately by 66% and 77% of college students in 2018, and 70% and 68% of college students in 2019. This session offered a chance for medical college students to be uncovered to some of the complicated moral and psychosocial points which will come up with genetic testing for liver illness and to contemplate how to navigate them. Using an viewers response system throughout the lecture made the session extra interactive and allowed the instructor to appropriate errors and train primarily based on the responses.
Development and implementation of an electronic medical record module to track genetic testing results

A potential cohort research assessing medical referral administration & workforce allocation inside a UK regional medical genetics service.

Ensuring affected person entry to genomic info in the face of growing demand requires clinicians to develop revolutionary methods of working. This paper presents the primary empirical potential observational cohort research of UK multi-disciplinary genetic service supply. It describes and explores collaborative working practices together with the utilisation and position of medical geneticists and non-medical genetic counsellors. Six hundred and fifty new sufferers referred to a regional genetics service had been tracked via 850 medical contacts till discharge. Referral selections concerning allocation of lead well being skilled assigned to the case had been monitored, together with the use of preliminary medical contact tips.

Significant variations had been discovered in the circumstances led by genetic counsellors and people led by medical geneticists. Around a sixth, 16.8% (109/650) of referrals had been handled by a letter again to the referrer or re-directed to one other service supplier and 14.8% (80/541) of the remaining sufferers selected not to schedule an appointment. Of the remaining 461 sufferers, genetic counsellors had been allotted as lead well being skilled for 46.2% (213/461). An additional 61 sufferers didn’t attend. Of those that did, 86.3% (345/400) had been discharged after one or two appointments.

Genetic counsellors contributed to 95% (784/825) of complete affected person contacts. They offered 93.7% (395/432) of preliminary contacts and 26.8% (106/395) of sufferers had been discharged at that time. The info from this research knowledgeable a deliberate service re-design. More analysis is required to assess the effectiveness and effectivity of completely different fashions of collaborative multi-disciplinary working inside genetics services.

Total RNA - Rat Normal Tissue: Kidney

R1434142-50 50 ug
EUR 156

Genomic DNA - Rat Normal Tissue: Kidney

D1434142 100 ug
EUR 329

Rat normal kidney tissue array

TR071a each
EUR 48
Description: Rat normal kidney tissue array, 6 cases/24 cores, replacing TR071

Normal kidney and normal adjacent kidney tissue array

KDN241a each
EUR 138
Description: Normal kidney and normal adjacent kidney tissue array, 24 cases/ 24 cores

Matched Pair - cDNA - Human Primary Tumor and Normal Tissue: Kidney

C8235142-PP 10 reactions x2
EUR 583

Kidney cancer tissue array with normal Kidney tissue

KD2082a each
EUR 474
Description: Kidney cancer tissue array with normal Kidney tissue, including TNM and pathology grade, 96 cases/192 cores, replacing KD2082

Kidney Tissue Slide (Normal)

10-401-10um 10 um
EUR 241.8

Kidney Tissue Slide (Normal)

10-401-4um 4 um
EUR 216.6

Normal kidney tissue array

KD803 each
EUR 354
Description: Normal kidney tissue array, replacing BN07012, 80 cases/80 cores

Normal kidney tissue array

KDN242 each
EUR 72
Description: Normal kidney tissue array, 24 cases/24 cores

Kidney Tissue Lysate (Normal)

1706-02 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-03 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-04 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-05 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Rat Tissue Lysate Kidney Medulla Normal

GWB-F5DEBF 0.15 mg Ask for price

Kidney cancer tissue array with adjacent normal kidney tissue

BC07015b each
EUR 168
Description: Kidney cancer tissue array with adjacent normal kidney tissue, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing BC07015a

Total RNA - Mouse Normal Tissue: Kidney

R1334142-50 50 ug
EUR 156

Genomic DNA - Mouse Normal Tissue: Kidney

D1334142 100 ug
EUR 329

Total Protein - Mouse Normal Tissue: Kidney

P1334142 1 mg
EUR 216

Tissue Lysate (Normal) Human Kidney

GWB-FEAC28 0.15 mg Ask for price

Kidney cancer tissue array with matched adjacent normal kidney tissue

KD901a each
EUR 258
Description: Kidney cancer tissue array with matched adjacent normal kidney tissue, including TNM, clinical stage and pathology grade, 40 cases/90 cores, replacing KD901

Kidney tumour with normal tissue array

KD2001 each
EUR 474
Description: Kidney tumour with normal tissue array, including Clear cell carcinoma (CCRCC), Sarcomatoid carcinoma, Papillary renal cell carcinoma (PRCC), Chromopobe carcinoma(crcc), Invasive low grade urothelial carcinoma, with Isup Grade, TNM/Stage (AJCC 8th edition), 100 cases/200 cores (core size 1.0mm),replacing BC07114

Total RNA - Human Adult Normal Tissue: Kidney

R1234142-50 50 ug
EUR 221

Kidney cancer tissue array with normal tissues

KD2083 each
EUR 474
Description: Kidney cancer tissue array with normal tissues, with stage and grade info, 69 cases/208 cores

Kidney cancer tissue array with normal tissues

KD721 each
EUR 168
Description: Kidney cancer tissue array with normal tissues, 24 cases/72 cores

Mouse Normal Tissue: Kidney Whole Cell Lysate

MNK-100 1 mg
EUR 628.8

Mouse Normal Tissue: Kidney Whole Cell Lysate

MNK-50 50 ug
EUR 196.8

Total RNA - Monkey (Rhesus) Normal Tissue: Kidney

R1534142-50 50 ug
EUR 229

Kidney tumor tissue array with normal tissue as control

KD961 each
EUR 258
Description: Kidney tumor tissue array with normal tissue as control, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Total Protein - Human Adult Normal Tissue: Kidney

P1234142 1 mg
EUR 216

Kidney cancer tissue array with normal tissue as control

KD962 each
EUR 258
Description: Kidney cancer tissue array with normal tissue as control, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Rat Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80263 1 x 100 ml Ask for price

Total RNA - Monkey (Cynomolgus) Normal Tissue: Kidney

R1534142-Cy 50 ug
EUR 229

Adjacent normal kidney tissue and cancer tissue array

BN07011b each
EUR 203
Description: Adjacent normal kidney tissue and cancer tissue array, including pathology grade, TNM and clinical stage, 20 cases/54 cores, replacing BN07011

Membrane Protein - Human Adult Normal Tissue: Kidney

P3234142 0.1 mg
EUR 311

Kidney cancer (grade I) tissue array with matched adjacent normal kidney tissue

KD701a each
EUR 234
Description: Kidney cancer (grade I) tissue array with matched adjacent normal kidney tissue, including TNM, clinical stage and pathology grade, 35 cases/70 cores, replacing KD701

FFPE Total RNA - Human Adult Normal Tissue: Kidney

R2234142 1 ug
EUR 744

Kidney cancer tissue array with matched adjacent normal tissue

KD321a each
EUR 198
Description: Kidney cancer tissue array with matched adjacent normal tissue, including TNM, clinical stage and pathology ISUP grade, 16 cases/32 cores, replacing KD321

Kidney cancer with matched adjacent normal kidney tissue array

KD603 each
EUR 204
Description: Kidney cancer with matched adjacent normal kidney tissue array, containing metastatic clear cell carcinoma, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 33 cases/61 cores

Kidney cancer tissue array with matched normal adjacent or caner adjacent kidney tissue

Kid-060Sur01 each
EUR 954
Description: Kidney cancer tissue array with matched normal adjacent or caner adjacent kidney tissue, including TNM, ISUP grade and survival data, 30 cases/60 cores

Human Adult Kidney (Normal) Whole tissue lysate

HAL-1305 1 mg
EUR 628.8

Monkey (Cyno.) Normal Kidney Whole tissue lysate

MCL-1190 1 mg
EUR 628.8

Monkey (Rhesus) Normal Kidney Whole tissue lysate

MRL-1301 1 mg
EUR 628.8

Frozen Tissue Section - Human Adult Normal: Kidney

T1234142 5 slides
EUR 377

Kidney Tumor Tissue Array - 12 cases of kidney cancer paired with adjacent normal tissues

Z7020053 5 slides
EUR 1125.6
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Adult Normal: Kidney

T2234142 5 slides
EUR 204

Human Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80075 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80171 1 x 100 ml Ask for price

Multiple Kidney cancer tissue array with normal tissue control from autopsy

KD483 each
EUR 168
Description: Multiple Kidney cancer tissue array with normal tissue control from autopsy, 48 cases/48 cores, with stage and grade data

Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Kidney

D8235142-PP-10 2x10 ug
EUR 478

Rat Kidney Tissue Preparation Buffer 6: Normal Renal Firbroblasts

9-80267 1 x 100 ml Ask for price

Total RNA - Human Adult Normal Tissue 5 Donor Pool: Kidney

R1234142-P 50 ug
EUR 443

Rat Normal Kidney tissue (single section per slide) (5 slides/pack)

RaFPT007 5 slides
EUR 150

Kidney Tissue Slides, Normal Rat Paraffin Sections, 5 slides/pack

TS-R5405 -
EUR 145

High density tissue array (70 cases/208 cores) of kidney cancer and normal tissue

KD208 each
EUR 546
Description: High density tissue array (70 cases/208 cores) of kidney cancer and normal tissue

Genomic DNA - Human Adult Normal Tissue: Kidney, from a single donor

D1234142 100 ug
EUR 329

Matched Pair - Total RNA - Human Primary Tumor and Normal Tissue: Kidney

R8235142-PP-10 2x10 ug
EUR 500

Mouse Kidney Tissue Preparation Buffer 3: Normal Podocytes

9-80172 1 x 100 ml Ask for price

cDNA - Rat Normal Tissue: Lung

C1434152 40 reactions
EUR 424

Multiple Kidney cancer test tissue array with unmatched normal adjacent tissue

KD242 each
EUR 48
Description: Multiple Kidney cancer test tissue array with unmatched normal adjacent tissue, 10 cases/24 cores

cDNA - Rat Normal Tissue: Brain

C1434035 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Colon

C1434090 40 reactions
EUR 636

cDNA - Rat Normal Tissue: Heart

C1434122 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Liver

C1434149 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Rectum

C1434206 40 reactions
EUR 636

cDNA - Rat Normal Tissue: Spleen

C1434246 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Testis

C1434260 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Adipose

C1434003 40 reactions
EUR 636

cDNA - Rat Normal Tissue: Bladder

C1434010 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Stomach

C1434248 40 reactions
EUR 424

Kidney cancer with matched cancer adjacent normal tissue test array

KD241 each
EUR 48
Description: Kidney cancer with matched cancer adjacent normal tissue test array, including TNM and clinical stage, 6 cases/24 cores

Kidney cancer with matched cancer adjacent normal tissue test array

KD241a each
EUR 66
Description: Kidney cancer with matched cancer adjacent normal tissue test array, including TNM and clinical stage, 6 cases/24 cores, replacing KD241

cDNA - Rat Normal Tissue: Placenta

C1434200 40 reactions
EUR 636

Rat Kidney Tissue Preparation Buffer 1: Normal Glomerular Endothelial Cells

9-80262 1 x 100 ml Ask for price

Matched Pair - Total Protein - Human Primary Tumor and Normal Tissue (PP): Kidney

P8235142-PP 0.2 mg x2
EUR 716

Human Kidney Tissue Preparation Buffer 6: Normal Renal Podocytes

9-80079 1 x 100 ml Ask for price

Rat Kidney Tissue Preparation Buffer 5: Normal Renal Artery Endothelial Cells

9-80266 1 x 100 ml Ask for price

Rat Kidney Tissue Preparation Buffer 8: Normal Renal Tubular Epithelial Cells

9-80269 1 x 100 ml Ask for price

Human Kidney Tissue Preparation Buffer 4: Normal Renal Firbroblasts

9-80077 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 5: Normal Renal Firbroblasts

9-80174 1 x 100 ml Ask for price

Kidney cancer tissue array with matched normal adjacent tissue and metastatic carcinoma

KD951a each
EUR 1434
Description: Kidney cancer tissue array with matched normal adjacent tissue and metastatic carcinoma, with TNM, clinical stage, pathology grade and survival data, 32 cases/95 cores,replacing KD951

Kidney Tissue Slides, Normal Human Paraffin Sections, 5 slides/pack

TS-H5013 -
EUR 145

Kidney Tissue Slides, Normal Mouse Paraffin Sections, 5 slides/pack

TS-M5203 -
EUR 145

Human Kidney Tissue Preparation Buffer 5: Normal Renal Mesangial Cells

9-80078 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 6: Normal Renal Mesangial Cells

9-80175 1 x 100 ml Ask for price

cDNA - Rat Normal Tissue: Skeletal Muscle

C1434171 40 reactions
EUR 424

cDNA - Rat Normal Tissue: Small Intestine

C1434226 40 reactions
EUR 636

cDNA - Human Tumor Tissue: Kidney

C1235142 40 reactions
EUR 636

Matched Pair (Normal and Carcinoma) Human Kidney Tissue Array (5 slides/pk)

TAS-1007 1 pk
EUR 343.2

30 case of Kidney clear cell carcinoma with 5 of NAT and 5 normal tissue array

KD805 each
EUR 258
Description: 30 case of Kidney clear cell carcinoma with 5 of NAT and 5 normal tissue array, 40 cases/80 cores

Human Kidney Tissue Preparation Buffer 1: Normal Glomerular Endothelial Cells

9-80074 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 1: Normal Glomerular Endothelial Cells

9-80170 1 x 100 ml Ask for price

Matched Pair - Frozen Tissue Section - Human Primary Tumor and Normal (PP): Kidney

T6235142-PP 5 slides x2
EUR 595

Paired Cancer and Normal Kidney Paraffin Tissue (FFPE) Section (5 slides/pack)

NCT176 5 slides
EUR 300

Human Kidney Tissue Preparation Buffer 3: Normal Renal Artery Endothelial Cells

9-80076 1 x 100 ml Ask for price

Human Kidney Tissue Preparation Buffer 7: Normal Renal Tubular Epithelial Cells

9-80080 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 4: Normal Renal Artery Endothelial Cells

9-80173 1 x 100 ml Ask for price

Mouse Kidney Tissue Preparation Buffer 8: Normal Renal Tubular Epithelial Cells

9-80177 1 x 100 ml Ask for price

Matched Pair - Paraffin Tissue Section - Human Primary Tumor and Normal (PP): Kidney

T8235142-PP 5 slides x2
EUR 383

cDNA - Dog Normal Tissue: Lung

C1734152 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Brain

C1734035 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Cecum

C1734089 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Heart

C1734122 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Liver

C1734149 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Lung

C1334152 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Rectum

C1734206 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Testis

C1734260 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Brain

C1334035 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Colon

C1334090 40 reactions
EUR 636

cDNA - Mouse Normal Tissue: Heart

C1334122 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Liver

C1334149 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Bladder

C1734010 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Trachea

C1734160 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Stomach

C1734248 40 reactions
EUR 424

Frozen Tissue Array - 37 Different Kidney Tumors and 3 Corresponding Normal Controls

T6235142-1 1 slide
EUR 761

Frozen Tissue Array - 37 Different Kidney Tumors and 3 Corresponding Normal Controls

T6235142-5 5 slides
EUR 2500

cDNA - Mouse Normal Tissue: Rectum

C1334206 40 reactions
EUR 636

cDNA - Mouse Normal Tissue: Spleen

C1334246 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Testis

C1334260 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Pancreas

C1734188 40 reactions
EUR 424

cDNA - Plant Normal Tissue: cDNA - Plant: Corn

C1634330 40 reactions
EUR 741

cDNA - Plant Normal Tissue: cDNA - Plant: Rice

C1634360 40 reactions
EUR 741

cDNA - Plant Normal Tissue: cDNA - Plant: Wheat

C1634390 40 reactions
EUR 741

cDNA - Mouse Normal Tissue: Adipose

C1334003 40 reactions
EUR 636

cDNA - Mouse Normal Tissue: Bladder

C1334010 40 reactions
EUR 424

cDNA - Mouse Normal Tissue: Stomach

C1334248 40 reactions
EUR 424

cDNA - Dog Normal Tissue: Esophagus

C1734106 40 reactions
EUR 424

cDNA - Human Diabetic Diseased Tissue: Kidney

C1236142Dia 40 reactions
EUR 802

cDNA - Plant Normal Tissue: cDNA - Plant: Orange

C1634340 40 reactions
EUR 741

cDNA - Plant Normal Tissue: cDNA - Plant: Potato

C1634350 40 reactions
EUR 741

cDNA - Mouse Normal Tissue: Placenta

C1334200 40 reactions
EUR 636

Kidney Tumor Tissue Array - Duplicated 70 cases covering all the common types of kidney cancer and 5 cases of normal and

Z7020052 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Glycogen is the storage kind of glucose in animal cells. Its degradation can quickly present gasoline for vitality manufacturing (notably necessary in muscle), or replenish blood glucose throughout fasting by the liver. Genetic defects of glycogen metabolism give rise to glycogen storage illnesses (GSDs), manifesting histologically in irregular amount or high quality of glycogen in the cells. GSDs might be brought on by defects of proteins collaborating in the synthesis or degradation of glycogen itself, in the glycolytic degradation of glucose phosphates in muscle and erythrocytes, in the discharge of glucose from liver and kidney into the bloodstream, in the clearance of glycogen from lysosomes (all, “main GSDs”), or in the management of these pathways (“secondary GSDs”).